2-(2-Methoxyphenoxy)-terephthalic acid dimethyl ester → 7-Fluoro-9-oxo-9H-xanthene-3-carboxylic acid methyl ester

HRID 733400Notes

Reaction equation

HRID 733400 reaction equation
CO[C:3](=[O:22])[C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][C:5]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1.COC(=O)C1C=CC(C(OC)=O)=CC=1OC1C=CC=CC=1OC>>[CH3:11][O:10][C:8]([C:7]1[CH:12]=[CH:13][C:4]2[C:3](=[O:22])[C:16]3[C:15]([O:14][C:5]=2[CH:6]=1)=[CH:20][CH:19]=[C:18]([F:21])[CH:17]=3)=[O:9]

Participants

3

Reactant 2

HCID 574366712-(2-Methoxyphenoxy)-terephthalic acid dimethyl ester2×HCID 578392532-(4-Fluorophenoxy)-terephthalic acid dimethyl ester

Product 1

HCID 578392387-Fluoro-9-oxo-9H-xanthene-3-carboxylic acid methyl ester

Procedure

Using an adaptation of the method described in Procedure 15, substituting 2-(4-fluorophenoxy)-terephthalic acid dimethyl ester, 1e for 2-(2-methoxyphenoxy)-terephthalic acid dimethyl ester, 1c, the title compound 7-fluoro-9-oxo-9H-xanthene-3-carboxylic acid methyl ester, 2e was obtained. MS m/z (MH+) 272.9.

Sources & evidence

ORD record
ord-12062e37da4d46b0970e8326d273ccef
Source dataset
uspto-grants-2009_09
Patent number
US07589104B2

Reaction notes

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