HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) → 7-Fluoro-9-oxo-9H-xanthene-3-carboxylic acid diethylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | 5-methoxy-9-oxo-9H-xanthene-3-carboxylic acid | HCID 57436673 | — |
| Reactant | 7-Fluoro-9-oxo-9H-xanthene-3-carboxylic acid | HCID 57839237 | — |
| Reactant | 5-Bromo-9-oxo-9H-xanthene-3-carboxylic acid | HCID 57839245 | — |
| Product | 7-Fluoro-9-oxo-9H-xanthene-3-carboxylic acid diethylamide | HCID 57839235 | — |
Reaction Steps
Using an adaptation of the method described in Procedure 16, substituting 7-fluoro-9-oxo-9H-xanthene-3-carboxylic acid, 3e for 5-methoxy-9-oxo-9H-xanthene-3-carboxylic acid, 3d, and HATU for HBTU, the title compound 7-fluoro-9-oxo-9H-xanthene-3-carboxylic acid diethylamide, 4e was obtained. MS m/z (MH+) 314.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589104B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c591f457086b4971a3173f7488ad8725 |
| Source note | uspto-grants-2009_09 |