HRID733526

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5375564

未命名化合物

结构：CCCCCCCCC#Cc1ccc(CNc2ccc3c(c2)C(=O)OC(C)(C)O3)cc1

HCID11212285

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCC#Cc1ccc(CN(C(=O)/C=C/c2cccc(C(F)(F)F)c2)c2ccc3c(c2)C(=O)OC(C)(C)O3)cc1

HCID57841311

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure E using 6-[(4-dec-1-ynylbenzyl)amino]-2,2-dimethyl-4H-1,3-benzodioxin-4-one and (2E)-3-[3-(trifluoromethyl)phenyl]acryloyl chloride. HPLC, Rt: 6.6 min (purity: 87.4%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d118cdb2a064483bbcd68d35f59281cf
来源数据集: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07589232B2
来源说明: uspto-grants-2009_09

反应 SMILES

[C:1]([C:11]1[CH:31]=[CH:30][C:14]([CH2:15][NH:16][C:17]2[CH:29]=[CH:28][C:20]3[O:21][C:22]([CH3:27])([CH3:26])[O:23][C:24](=[O:25])[C:19]=3[CH:18]=2)=[CH:13][CH:12]=1)#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[F:32][C:33]([F:46])([F:45])[C:34]1[CH:35]=[C:36](/[CH:40]=[CH:41]/[C:42](Cl)=[O:43])[CH:37]=[CH:38][CH:39]=1>>[C:1]([C:11]1[CH:31]=[CH:30][C:14]([CH2:15][N:16]([C:17]2[CH:29]=[CH:28][C:20]3[O:21][C:22]([CH3:26])([CH3:27])[O:23][C:24](=[O:25])[C:19]=3[CH:18]=2)[C:42](=[O:43])/[CH:41]=[CH:40]/[C:36]2[CH:37]=[CH:38][CH:39]=[C:34]([C:33]([F:45])([F:46])[F:32])[CH:35]=2)=[CH:13][CH:12]=1)#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]