4-Hexylbenzoyl chloride → HCID 57841402, compound

HRID 733559Notes

Reaction equation

HRID 733559 reaction equation
Cl.[CH2:2]([C:6]1[CH:11]=[CH:10][C:9]([C:12]#[C:13][C:14]2[CH:34]=[CH:33][C:17]([CH2:18][NH:19][C:20]3[CH:32]=[CH:31][C:23]4[O:24][C:25]([CH3:30])([CH3:29])[O:26][C:27](=[O:28])[C:22]=4[CH:21]=3)=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:3][CH2:4][CH3:5].[CH2:35]([C:41]1[CH:49]=[CH:48][C:44]([C:45](Cl)=[O:46])=[CH:43][CH:42]=1)[CH2:36][CH2:37][CH2:38][CH2:39][CH3:40]>>[CH2:2]([C:6]1[CH:7]=[CH:8][C:9]([C:12]#[C:13][C:14]2[CH:34]=[CH:33][C:17]([CH2:18][N:19]([C:20]3[CH:32]=[CH:31][C:23]4[O:24][C:25]([CH3:30])([CH3:29])[O:26][C:27](=[O:28])[C:22]=4[CH:21]=3)[C:45](=[O:46])[C:44]3[CH:48]=[CH:49][C:41]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])=[CH:42][CH:43]=3)=[CH:16][CH:15]=2)=[CH:10][CH:11]=1)[CH2:3][CH2:4][CH3:5]

Participants

3

Reactant 2

HCID 1708634-Hexylbenzoyl chlorideHCID 684196986-({4-[(4-butylphenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one hydrochloride

Product 1

HCID 57841402HCID 57841402, compound

Procedure

The titled compound was prepared following the procedure K using 6-({4-[(4-butylphenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one hydrochloride and 4-hexylbenzoyl chloride as a yellow oil (85%). HPLC, Rt: 6.45 min (Purity: 99.8%).

Sources & evidence

ORD record
ord-5732528423ae4ed2aff0b271679d8976
Source dataset
uspto-grants-2009_09
Patent number
US07589232B2

Reaction notes

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