Sodium Hydroxide → HCID 16040641, compound

Participants

Reaction Steps

The titled compound was prepared following the procedure C using N-{4-[(4-butylphenyl)ethynyl]benzyl}-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-6-yl)-1-benzothiophene-2-carboxamide and NaOH 5M aq. in the presence of EtOH as a beige powder (37%). 1H NMR (CDCl3/MeOD 35:1, 300 MHz) δ 7.67 (m, 3H), 7.45-7.24 (m, 9H) 7.11 (m, 3H), 6.91 (d, J=9 Hz, 1H) 5.05 (s, 2H), 2.61 (t, J=7.5 Hz, 2H), 1.58 (m, 2H), 1.34 (m, 2H), 0.91 (t, J=7.2 Hz, 3H). M− (ESI): 558.3; M+ (ESI): 560.1 HPLC, Rt: 5.62 min (Purity: 99.2%).

Provenance & Evidence