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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 733584Generated: October 27, 2026

Pyrazole-4-carboxylic acid → methyl (4-{[{4-[(4-butylphenyl)ethynyl]benzyl}(1H-pyrazol-4-ylcarbonyl)amino]methyl}phenoxy)acetate

https://huagongshe.com/reaction/733584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazole-4-carboxylic acidHCID 3015937—
ReactantMethyl {4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]phenoxy}acetateHCID 57554567—
Productmethyl (4-{[{4-[(4-butylphenyl)ethynyl]benzyl}(1H-pyrazol-4-ylcarbonyl)amino]methyl}phenoxy)acetateHCID 57841328—

Reaction Steps

The titled compound was prepared following the procedure H using methyl {4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]phenoxy}acetate and 1H-pyrazole-4-carboxylic acid as a colorless oil (95%). HPLC, Rt: 5.15 min (Purity: 69.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07589232B2
Source datasetuspto-grants-2009_09
ORD IDord-83028ab670664eaa9a422eb6c0504a1c
Source noteuspto-grants-2009_09