4-tert-Butylbenzoyl chloride → Methyl 4-[((4-tert-butylbenzoyl){4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]benzoate

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The titled compound was prepared following the procedure E using methyl 4-[({4-[(4-butylphenyl)ethynyl]benzyl}amino)methyl]benzoate and 4-tert-butylbenzoyl chloride as a colorless oil (63%). 1H NMR (CDCl3, 300 MHz) δ 8.02 (d, J=8.3 Hz, 2H), 7.50 (d, J=8.3 Hz, 2H), 7.48-7.29 (m, 7H), 7.28-7.07 (m, 5H), 4.80-4.62 (m, 2H), 4.55-4.40 (m, 2H), 3.92 (s, 3H), 2.61 (t, J=7.7 Hz, 2H), 1.66-1.53 (m, 2H), 1.40-1.23 (m, 11H), 0.92 (t, J=7.4 Hz, 3H). M+ (ESI): 572.5. HPLC, Rt: 6.22 min (Purity: 99.5%).

Provenance & Evidence