HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-[{4-[(4-Chlorophenyl)ethynyl]benzyl}(4-heptylbenzoyl)amino]-2-hydroxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-{4-[(4-chlorophenyl)ethynyl]benzyl)-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-6-yl)-4-heptylbenzamide | HCID 57841350 | — |
| Product | 5-[{4-[(4-Chlorophenyl)ethynyl]benzyl}(4-heptylbenzoyl)amino]-2-hydroxybenzoic acid | HCID 11467324 | — |
Reaction Steps
The titled compound was prepared following the procedure C using N-{4-[(4-chlorophenyl)ethynyl]benzyl}-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-6-yl)-4-heptylbenzamide and NaOH as a white solid (67%). M− (ESI): 577.8; M+ (ESI): 580.1. HPLC, Rt: 5.89 min (Purity: 92.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07589232B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-d3b62dcf455b49b6917b20a478b66075 |
| Source note | uspto-grants-2009_09 |