p-Anisoyl chloride → HCID 57841376, compound

HRID 733613Notes

Reaction equation

HRID 733613 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]#[C:9][C:10]2[CH:30]=[CH:29][C:13]([CH2:14][NH:15][C:16]3[CH:28]=[CH:27][C:19]4[O:20][C:21]([CH3:26])([CH3:25])[O:22][C:23](=[O:24])[C:18]=4[CH:17]=3)=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.[CH3:31][O:32][C:33]1[CH:41]=[CH:40][C:36]([C:37](Cl)=[O:38])=[CH:35][CH:34]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]#[C:9][C:10]2[CH:30]=[CH:29][C:13]([CH2:14][N:15]([C:16]3[CH:28]=[CH:27][C:19]4[O:20][C:21]([CH3:26])([CH3:25])[O:22][C:23](=[O:24])[C:18]=4[CH:17]=3)[C:37](=[O:38])[C:36]3[CH:40]=[CH:41][C:33]([O:32][CH3:31])=[CH:34][CH:35]=3)=[CH:12][CH:11]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 111543016-({4-[(4-chlorophenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one

Product 1

HCID 57841376HCID 57841376, compound

Procedure

The titled compound was prepared following the procedure E using 6-({4-[(4-chlorophenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one and 4-methoxybenzoyl chloride as a yellow oil (91%). M+ (ESI): 552. HPLC, Rt: 5.65 min (Purity: 98.5%).

Sources & evidence

ORD record
ord-090e20ccce6f4c32b09049cfc5583da9
Source dataset
uspto-grants-2009_09
Patent number
US07589232B2

Reaction notes

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