HCID 57841372, compound → 4-[{4-[(4-Butylphenyl)ethynyl]benzyl}(cyclohexylcarbonyl)amino]-2-hydroxybenzoic acid

Participants

Reaction Steps

The titled compound was prepared following the procedure C using N-{4-[(4-butylphenyl)ethynyl]benzyl}-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-7-yl)cyclohexanecarboxamide in the presence of THF as a brown powder (78%). 1H NMR (CDCl3, 300 MHz) δ 10.64 (s, 1H), 7.85 (d, J=8.7 Hz, 1H), 7.41 (m, 4H), 7.14 (m, 4H), 6.68 (m, 1H), 6.52 (d, J=8.7 Hz, 1H), 4.87 (s, 2H), 2.60 (t, J=7.1 Hz, 2H), 2.25 (m, 1H), 1.80-1.50 (m, 8H), 1.41-0.95 (m, 6H), 0.91 (t, J=7.3 Hz, 3H). M− (ESI): 507.9. M+ (ESI): 510.0. HPLC, Rt: 5.92 min (Purity: 100%).

Provenance & Evidence