Hexanoyl chloride → HCID 57841362, compound

Participants

Reaction Steps

The titled compound was prepared following the procedure M using 7-({4-[(4-butylphenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one and hexanoyl chloride as all orange oil (69%). 1H NMR (CDCl3, 300 MHz) δ 7.92 (d, J=8.3 Hz, 1H), 7.41 (m, 4H), 7.14 (m, 4H), 6.78 (d, J=8.3 Hz, 1H), 6.59 (s, 1H), 4.89 (s, 2H), 2.60 (t, J=7.7 Hz, 2H), 2.14 (t, J=7.3 Hz, 2H), 1.71 (s, 6H), 1.66-1.51 (m, 4H), 1.43-1.12 (m, 8H), 0.91 (t, J=7.3 Hz, 3H). 0.84 (t, J=6.7 Hz, 3H). M+ (ESI): 538.2. HPLC, Rt: 6.34 min (Purity: 99.4%).

Provenance & Evidence