3-Cyclopentylpropionyl chloride → HCID 57841330, compound

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Reaction Steps

The title compound was prepared following the procedure B using 7-({4-[(4-methoxyphenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one and 3-cyclopentylpropionyl chloride as a beige solid (63%). 1H NMR (CDCl3) δ 7.91 (d, J=8.3 Hz, 1H), 7.41 (m, 4H), 7.12 (d, J=8.1 Hz, 2H), 6.85 (d, J=8.5 Hz, 2H), 6.76 (d, J=8.1 Hz, 1H), 6.59 (s, 1H), 4.87 (s, 2H), 3.80 (s, 3H), 2.15 (t, J=6.9 Hz, 2H), 1.70 (s, 6H), 1.40-1.61 (m, 9H), 0.95 (m, 2H). HPLC, Rt: 5.78 min (purity: 99.3%).

Provenance & Evidence