5-Phenyl-1-pentyne → HCID 57841352, compound

HRID 733650Notes

Reaction equation

HRID 733650 reaction equation
Br[C:2]1[CH:31]=[CH:30][C:5]([CH2:6][N:7]([C:17]2[CH:18]=[CH:19][C:20]3[C:25](=[O:26])[O:24][C:23]([CH3:28])([CH3:27])[O:22][C:21]=3[CH:29]=2)[C:8](=[O:16])[CH2:9][CH2:10][CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:4][CH:3]=1.[C:32]1([CH2:38][CH2:39][CH2:40][C:41]#[CH:42])[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH:11]1([CH2:10][CH2:9][C:8]([N:7]([C:17]2[CH:18]=[CH:19][C:20]3[C:25](=[O:26])[O:24][C:23]([CH3:28])([CH3:27])[O:22][C:21]=3[CH:29]=2)[CH2:6][C:5]2[CH:4]=[CH:3][C:2]([C:42]#[C:41][CH2:40][CH2:39][CH2:38][C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)=[CH:31][CH:30]=2)=[O:16])[CH2:12][CH2:13][CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 745735-Phenyl-1-pentyneHCID 57841396N-(4-bromobenzyl)-3-cyclopentyl-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-7-yl)propanamide

Product 1

HCID 57841352HCID 57841352, compound

Procedure

The titled compound was prepared following the procedure N using N-(4-bromobenzyl)-3-cyclopentyl-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-7-yl)propanamide and 5-phenyl-1-pentyne as a yellow oil (54%). M+ (ESI): 550.2. HPLC, Rt: 5.96 min (Purity: 94.9%).

Sources & evidence

ORD record
ord-a0575960c02b40e0bd278773a392aa77
Source dataset
uspto-grants-2009_09
Patent number
US07589232B2

Reaction notes

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