Methanesulfonic Acid → HCID 68866945, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 7-chloro-3-methyl-4-(1-morpholin-4-yl-methanoyl)-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester (66 mg), cyclohexylamine (80 ul), and methanesulfonic acid (45 ul) in 1,4-dioxane (1 ml) was heated under microwave conditions at 180° C. for 30 minutes. Cyclohexylamine (600 ul in total) was added and the mixture heated under microwave conditions at 180° C. for 2.5 h. The solid mass obtained was purified as described in Example 11(c) to afford the title compound (31 mg).

Provenance & Evidence