Isobutylamine → HCID 57841037, compound

HRID 733682Notes

Reaction equation

[Cl:1][C:2]1[C:7]2[NH:8][CH:9]=[CH:10][C:6]=2[C:5]([C:11]([OH:13])=O)=[CH:4][N:3]=1.[CH2:14]([NH2:18])[CH:15]([CH3:17])[CH3:16]>>[CH2:14]([NH:18][C:11]([C:5]1[C:6]2[CH:10]=[CH:9][NH:8][C:7]=2[C:2]([Cl:1])=[N:3][CH:4]=1)=[O:13])[CH:15]([CH3:17])[CH3:16]

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 578408437-chloro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid

Product 1

HCID 57841037HCID 57841037, compound

Procedure

Prepared in a similar manner to Example 19 (e) from 7-chloro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid using isobutylamine (28 mg) instead of tetrahydro-pyran-4-ylmethylamine to give the title compound (38 mg).

Sources & evidence

ORD record: ord-08ae2604f259414b9c67cfbf86970428
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07589206B2

Reaction notes

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