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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 73385Generated: October 26, 2026

(Chloromethyl)sulfonyl chloride → 1-Chloro-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl) methane sulfonamide

https://huagongshe.com/reaction/73385

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Chloromethyl)sulfonyl chlorideHCID 77054—
Reactant5,6-difluoro-N1-(2-fluoro-4-iodophenyl)benzene-1,2-diamineHCID 59386306—
Product1-Chloro-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl) methane sulfonamideHCID 56953231—

Reaction Steps

According to the general procedure A, 5,6-difluoro-N1-(2-fluoro-4-iodophenyl)benzene-1,2-diamine was reacted with chloromethanesulfonyl chloride to obtain the desired product, m/z=475 [M−1]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829052B2
Source datasetuspto-grants-2014_09
ORD IDord-1934a3c7a8ea4d3fbe45d714dfbb9d65
Source noteuspto-grants-2014_09