HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Prop-2-en-1-yl)cyclopropane-1-sulfonyl chloride → 1-allyl-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl)cyclopropane-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Prop-2-en-1-yl)cyclopropane-1-sulfonyl chloride | HCID 44181959 | — |
| Reactant | 5,6-difluoro-N1-(2-fluoro-4-iodophenyl)benzene-1,2-diamine | HCID 59386306 | — |
| Product | 1-allyl-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl)cyclopropane-1-sulfonamide | HCID 59386322 | — |
Reaction Steps
According to the general procedure B, 5,6-difluoro-N1-(2-fluoro-4-iodophenyl)benzene-1,2-diamine was reacted with 1-allylcyclopropane-1-sulfonyl chloride to obtain the desired product. m/z=507 [M−1]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08829052B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-07d768243a10423285740e1e361c7e15 |
| Source note | uspto-grants-2014_09 |