Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 68817537, compound

HRID 734148Notes

Reaction equation

HRID 734148 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH:12]([OH:15])[CH2:13][OH:14])=[C:6]([CH3:16])[CH:5]=1)([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:29].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:29].[ClH:29].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH:12]([OH:15])[CH2:13][OH:14])=[C:6]([CH3:16])[CH:5]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104613HCID 23104613, compound

Product 1

HCID 68817537HCID 68817537, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 3-(4-nitro-2-methylphenylamino)propane-1,2-diol (7) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-087a86c38a5d4f4abfb8e071e8e1e355
Source dataset
uspto-grants-2009_09
Patent number
US07591860B2

Reaction notes

Loading…