HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoro-m-phenylenediamine dihydrochloride → 2-(4-Amino-3-methylphenylamino)propane-1,3-diol dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 2-(4-Nitro-3-methylphenylamino)propane-1,3-diol | HCID 23104596 | — |
| Catalyst | ZINC ammonium chloride water ethanol | HCID 131726756 | — |
| Product | 2-(4-Amino-3-methylphenylamino)propane-1,3-diol dihydrochloride | HCID 68816528 | — |
Reaction Steps
The 2-(4-nitro-3-methylphenylamino)propane-1,3-diol (11) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07591860B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-02cd26076f4944fcb1da7dcd39b0dc3f |
| Source note | uspto-grants-2009_09 |