Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 68816970, compound

HRID 734154Notes

Reaction equation

HRID 734154 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH:11]([CH2:14][OH:15])[CH2:12][OH:13])=[C:6]([CH3:16])[CH:5]=1)([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:29].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:29].[ClH:29].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH:11]([CH2:12][OH:13])[CH2:14][OH:15])=[C:6]([CH3:16])[CH:5]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 23104615HCID 23104615, compound

Product 1

HCID 68816970HCID 68816970, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 2-(4-nitro-2-methylphenylamino)propane-1,3-diol (13) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-7632e573be63486d80dee52b8699c0ff
Source dataset
uspto-grants-2009_09
Patent number
US07591860B2

Reaction notes

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