Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 68815965, compound

HRID 734156Notes

Reaction equation

HRID 734156 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH:11]([CH2:14][OH:15])[CH2:12][OH:13])=[CH:6][CH:5]=1)([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:28].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:28].[ClH:28].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH:11]([CH2:12][OH:13])[CH2:14][OH:15])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 11564737HCID 11564737, compound

Product 1

HCID 68815965HCID 68815965, compound

Reagents, catalysts & solvents 1

HCID 131726756ZINC ammonium chloride water ethanolCatalyst

Procedure

The 2-(4-nitrophenylamino)propane-1,3-diol (15) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-f8b246b3154d4837845e6b7c7370fe8d
Source dataset
uspto-grants-2009_09
Patent number
US07591860B2

Reaction notes

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