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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734158Generated: October 30, 2026

Tetrafluoro-m-phenylenediamine dihydrochloride → 2-[[2-(4-amino-2-methylphenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol Dihydrochloride

https://huagongshe.com/reaction/734158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrafluoro-m-phenylenediamine dihydrochlorideHCID 149026—
ReactantHCID 57841525HCID 57841525—
CatalystZINC ammonium chloride water ethanolHCID 131726756—
Product2-[[2-(4-amino-2-methylphenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol DihydrochlorideHCID 68820411—

Reaction Steps

The 2-[[2-(4-nitro-2-methylphenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol (17) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07591860B2
Source datasetuspto-grants-2009_09
ORD IDord-9b1285cf1063403ba209da9cfbe270a0
Source noteuspto-grants-2009_09