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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734160Generated: October 31, 2026

Tetrafluoro-m-phenylenediamine dihydrochloride → 2-[[2-(4-Aminophenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol dihydrochloride

https://huagongshe.com/reaction/734160

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrafluoro-m-phenylenediamine dihydrochlorideHCID 149026—
Reactant2-[[-(4-Nitrophenylamino)ethyl]-(2-hydroxyethyl)amino]ethanolHCID 57841523—
CatalystZINC ammonium chloride water ethanolHCID 131726756—
Product2-[[2-(4-Aminophenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol dihydrochlorideHCID 68817967—

Reaction Steps

The 2-[[2-(4-nitrophenylamino)ethyl]-(2-hydroxyethyl)amino]ethanol (19) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07591860B2
Source datasetuspto-grants-2009_09
ORD IDord-a7e2a5b927bc4c82965916859d9ff6db
Source noteuspto-grants-2009_09