HCID 57841526, compound → HCID 23104595, compound

HRID 734161Notes

Reaction equation

HRID 734161 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[NH:11][CH:12]([CH:15]([OH:31])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:13][OH:14]>C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl.[Zn].[Cl-].[NH4+].O.C(O)C>[NH2:8][C:6]1[CH:5]=[CH:4][C:3]([NH:11][CH:12]([CH:15]([OH:31])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:13][OH:14])=[C:2]([CH3:1])[CH:7]=1

Participants

4

Reactant 1

HCID 57841526HCID 57841526, compound

Product 1

HCID 23104595HCID 23104595, compound

Reagents, catalysts & solvents 2

HCID 131726756ZINC ammonium chloride water ethanolCatalystHCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideSolvent

Procedure

The 2-[(2-methyl-4-nitrophenyl)amino]octadecane-1,3-diol (21) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Sources & evidence

ORD record
ord-600fb09e99e949feb7b38c4cdd25b5b3
Source dataset
uspto-grants-2009_09
Patent number
US07591860B2

Reaction notes

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