HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline → (S)-4,4-dimethylpyrrolidine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline | HCID 67158944 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (S)-4,4-dimethylpyrrolidine-2-carboxylic acid | HCID 46907953 | — |
Reaction Steps
A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592316B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-4f3358791a2444a5ab857605c23461e2 |
| Source note | uspto-grants-2009_09 |