2-Methylpiperazine, (R)- → HCID 68816393, compound

HRID 734325Notes

Reaction equation

HRID 734325 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][CH:12]([C:15]([OH:17])=O)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)#[N:2].[CH3:18][C@@H:19]1[CH2:24][NH:23][CH2:22][CH2:21][NH:20]1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][CH:12]([C:15]([N:23]3[CH2:22][CH2:21][NH:20][C@H:19]([CH3:18])[CH2:24]3)=[O:17])[CH2:13][CH2:14]2)=[CH:7][CH:8]=1)#[N:2]

Participants

3

Reactant 2

HCID 73304342-Methylpiperazine, (R)-HCID 193914381-(4-Cyanophenyl)piperidine-4-carboxylic acid

Product 1

HCID 68816393HCID 68816393, compound

Procedure

The title compound (D16) was prepared from 1-(4-cyanophenyl)-piperidine4-carboxylic acid (D3) and (R)-2-methylpiperazine using the procedure of Description D15.

Sources & evidence

ORD record
ord-af8ca9e8c25a4ae4b115437c14c65c4c
Source dataset
uspto-grants-2009_09
Patent number
US07592347B2

Reaction notes

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