2,5-Dimethylpiperazine, trans- → HCID 86611237, compound

HRID 734326Notes

Reaction equation

HRID 734326 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][CH:12]([C:15]([OH:17])=O)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)#[N:2].[CH3:18][C@H:19]1[CH2:24][NH:23][C@H:22]([CH3:25])[CH2:21][NH:20]1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][CH:12]([C:15]([N:20]3[CH2:21][C@@H:22]([CH3:25])[NH:23][CH2:24][C@@H:19]3[CH3:18])=[O:17])[CH2:13][CH2:14]2)=[CH:7][CH:8]=1)#[N:2]

Participants

3

Procedure

The title compound (D17) was prepared from 1-(4-cyanophenyl)-piperidine4-carboxylic acid (D3) and (2S, 5R)-2,5-dimethylpiperazine using the procedure of Description D15.

Sources & evidence

ORD record
ord-d5f23ebde31a4e1b9d7b89d6db625d67
Source dataset
uspto-grants-2009_09
Patent number
US07592347B2

Reaction notes

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