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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734517Generated: October 25, 2026

Phenoxyacetyl chloride → N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-(phenyloxy)acetamide

https://huagongshe.com/reaction/734517

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetyl chlorideHCID 69703—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductN-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-(phenyloxy)acetamideHCID 5747828941%

Reaction Steps

The title compound was prepared in 41% yield according to the general procedure for the preparation of the amides (Method B) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and (phenyloxy)acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592346B2
Source datasetuspto-grants-2009_09
ORD IDord-83771d9d96734f37a6cc7ff9da3bb2e4
Source noteuspto-grants-2009_09