HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxyoxazole-2-carboxylic acid → 5-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,3-oxazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxyoxazole-2-carboxylic acid | HCID 1472232 | — |
| Reactant | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| Product | 5-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,3-oxazole-2-carboxamide | HCID 57478292 | 30% |
Reaction Steps
The title compound was prepared in 30% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 5-(methyloxy)-1,3-oxazole-2-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592346B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-b4611228260c46f2b2a31b76c089df9c |
| Source note | uspto-grants-2009_09 |