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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734524Generated: October 25, 2026

1,5-dimethyl-1H-pyrazole-3-carboxylic acid → 1,5-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-pyrazole-3-carboxamide

https://huagongshe.com/reaction/734524

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,5-dimethyl-1H-pyrazole-3-carboxylic acidHCID 587757—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
Product1,5-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1H-pyrazole-3-carboxamideHCID 6842660335%

Reaction Steps

The title compound was prepared in 35% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 1,5-dimethyl-1H-pyrazole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592346B2
Source datasetuspto-grants-2009_09
ORD IDord-89eb5cec48544ae58ab0efebfd3f8436
Source noteuspto-grants-2009_09