Phenyl chloroformate → HCID 131726636, compound

HRID 734529Notes

Reaction equation

HRID 734529 reaction equation
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[N:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][C:20]3[CH:21]=[C:22]([CH:24]=[CH:25][CH:26]=3)[NH2:23])[CH2:14][CH2:13]2)[N:3]=1.[CH:27]1[CH:32]=[CH:31][C:30]([O:33][C:34]([Cl:36])=[O:35])=[CH:29][CH:28]=1>>[ClH:36].[ClH:36].[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[N:12]2[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][C:20]3[CH:21]=[C:22]([NH:23][C:34](=[O:35])[O:33][C:30]4[CH:31]=[CH:32][CH:27]=[CH:28][CH:29]=4)[CH:24]=[CH:25][CH:26]=3)[CH2:16][CH2:17]2)[N:3]=1

Participants

3

Reactant 2

HCID 15891Phenyl chloroformateHCID 498521053-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline

Product 1

HCID 131726636HCID 131726636, compoundYield 59%

Procedure

The title compound was prepared in 59% yield according to the general procedure for the preparation of carbamates (Method D) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and phenyl chloridocarbonate.

Sources & evidence

ORD record
ord-b0c896ff844444eda2b603dd69bbb911
Source dataset
uspto-grants-2009_09
Patent number
US07592346B2

Reaction notes

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