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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734554Generated: October 31, 2026

Acetyl chloride → N-(3-{2-[4-(8-Fluoro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide

https://huagongshe.com/reaction/734554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantHCID 57444323HCID 57444323—
ProductN-(3-{2-[4-(8-Fluoro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamideHCID 5744431726%

Reaction Steps

The title compound was prepared in 26% yield according to the general procedure for the preparation of amides (Method B) starting from 3-{2-[4-(8-fluoro-2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592346B2
Source datasetuspto-grants-2009_09
ORD IDord-b37f135fbf764c3e9d07c0437c569c7f
Source noteuspto-grants-2009_09