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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 734585Generated: October 25, 2026

Methanesulfonyl chloride → N-(2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)methanesulfonamide dihydrochloride

https://huagongshe.com/reaction/734585

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 57444345—
ProductN-(2-(Methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)methanesulfonamide dihydrochlorideHCID 5747836872%

Reaction Steps

The title compound was prepared in 72% yield according to the general procedure for the preparation of amides (Method B) starting from 2-(methoxy)-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline and methanesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07592346B2
Source datasetuspto-grants-2009_09
ORD IDord-2bbf9b3bea82494abdda04ca646e7ea2
Source noteuspto-grants-2009_09