HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-2-pyrazolin-5-one → 5-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,4-dihydro-3H-pyrazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-2-pyrazolin-5-one | HCID 7920 | — |
| Reactant | 5-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinoline | HCID 57444355 | — |
| Product | 5-methyl-2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,4-dihydro-3H-pyrazol-3-one | HCID 57444375 | 58% |
Reaction Steps
The title compound was prepared in 58% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 5-{4-[2-(3-iodophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and 5-methyl-2,4-dihydro-3H-pyrazol-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592346B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-03a9eb02b7e046cf92f145a375554fcd |
| Source note | uspto-grants-2009_09 |