HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium, 4-methyl-1-(phenylmethyl)-, chloride (1:1) → 1-Benzyl-4-methyl-1,2,3,6-tetrahydropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium, 4-methyl-1-(phenylmethyl)-, chloride (1:1) | HCID 10856996 | — |
| Reactant | Ethyl acetate methanol ammonia | HCID 21873639 | — |
| Product | 1-Benzyl-4-methyl-1,2,3,6-tetrahydropyridine | HCID 6421572 | — |
Reaction Steps
The product was obtained analogously to IP 5b starting from 10.0 g (45.5 mmol) of 1-benzyl-4-methylpyridinium chloride. Yield: 7.15 g (84% of theoretical); C13H17N (M=187.281); calc.: molpeak (M+H)+: 188; found: molpeak (M+H)+: 188; Rf value: 0.95 (silica gel, EtOAc/MeOH/NH3 9:1:0.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-e3ad53ba131b46f0af5d55816a809fb8 |
| Source note | uspto-grants-2009_09 |