HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Nitrohexane → (3R,4S)-4-methyl-piperidine-3,4-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Nitrohexane | HCID 12589 | — |
| Reactant | (3R,4S)-1-benzyl-4-methylpiperidin-3,4-diol | HCID 69059860 | — |
| Product | (3R,4S)-4-methyl-piperidine-3,4-diol | HCID 55285415 | — |
Reaction Steps
The product was obtained analogously to IP 5d starting from 1.23 g (5.57 mmol) of (3R,4S)-1-benzyl-4-methylpiperidin-3,4-diol. Yield: 730 mg (quant. yield); C6H13NO2 (M=131.173); calc.: molpeak (M+H)+: 132; found: molpeak (M+H)+: 132; HPLC-MS: 0.93 minutes (method C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-4d7d7504d7564f1087599e2398547c39 |
| Source note | uspto-grants-2009_09 |