HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Chloroethyl)pyrrolidine hydrochloride → 1-[2-(4-Bromo-2-methoxyphenoxy)ethyl]pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Chloroethyl)pyrrolidine hydrochloride | HCID 81668 | — |
| Reactant | 4-Bromo-2-methoxyphenol | HCID 262234 | — |
| Product | 1-[2-(4-Bromo-2-methoxyphenoxy)ethyl]pyrrolidine | HCID 22994338 | — |
Reaction Steps
The product was obtained analogously to Example 24.1a starting from 4-bromo-2-methoxyphenol and 1-(2-chloroethyl)pyrrolidine hydrochloride. Yield: 3.96 g (45% of theoretical); C13H19BrNO2 (M=300.192); calc.: molpeak (M+H)+: 300/302 (Br); found: molpeak (M+H)+: 300/302 (Br); HPLC-MS: 4.67 minutes (method A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-ab5c9fbf59724ae586c30cd0eb674a38 |
| Source note | uspto-grants-2009_09 |