HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Iodobenzenemethanol → 3-(4-Hydroxymethylphenyl)propynoic acid-(4'-methoxybiphenyl-4-yl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Iodobenzenemethanol | HCID 53983225 | — |
| Reactant | Propynoic acid-(4'-methoxybiphenyl-4-yl)amide | HCID 86060753 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | 3-(4-Hydroxymethylphenyl)propynoic acid-(4'-methoxybiphenyl-4-yl)amide | HCID 68816004 | — |
Reaction Steps
Prepared analogously to Example 1.2.a. from iodobenzyl alcohol and propynoic acid-(4′-methoxybiphenyl-4-yl)amide. Yield: 0.21 g (22.9% of theory); C23H19NO3 (M=357.41); calc.: molecular ion peak (M+H)+: 358; found: molecular ion peak (M+H)+: 358; Rf value: 0.35 (silica gel, dichloromethane/ethanol (20:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-537a2f184c5a4124891e65a5c7665b0e |
| Source note | uspto-grants-2009_09 |