HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 65478349, compound → HCID 57845697, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 65478349 | HCID 65478349 | — |
| Reactant | Propynoic acid-(4'-chlorobiphenyl-4-yl)amide | HCID 86060771 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 57845697 | HCID 57845697 | — |
Reaction Steps
Prepared analogously to Example 1.1.d. from 1-(4-iodobenzyl)-4-methoxypiperidine and propynoic acid-(4′-chlorobiphenyl-4-yl)amide. Yield: 25 mg (13% of theory); melting point: 145° C.-146° C.; C28H27ClN2O2 (M=458.99); calc.: molecular ion peak (M+H)+: 459/461; found: molecular ion peak (M+H)+: 459/461; Rf value: 0.4 (silica gel, dichloromethane/methanol (10:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-dfe424bc6c79445db3cf5ba34847c9ad |
| Source note | uspto-grants-2009_09 |