HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia methanol dichloromethane → HCID 57845771, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Reactant | HCID 68816274 | HCID 68816274 | — |
| Reactant | Propynoic acid-(4'-chlorobiphenyl-4-yl)amide | HCID 86060771 | — |
| Product | HCID 57845771 | HCID 57845771 | — |
Reaction Steps
Prepared analogously to Example 1.1.d. from 1-(4-iodobenzyl)-4-pyrrolidin-1-ylpiperidine and propynoic acid-(4′-chlorobiphenyl-4-yl)amide. Yield: 15 mg (7% of theory); melting point: 191° C.-192° C.; C31H32ClN3O (M=498.07); calc.: molecular ion peak (M+H)+: 498/500; found: molecular ion peak (M+H)+: 498/500; Rf value: 0.45 (silica gel, dichloromethane/methanol/ammonia (10:1:0.1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-3b38a21a8bd1494d9e6a2d9f26521bc4 |
| Source note | uspto-grants-2009_09 |