4-(2-(Diethylamino)ethoxy)aniline → HCID 57845796, compound

Participants

Reaction Steps

Prepared analogously to Example 2.3.f. from 69 mg (0.33 mmol) of 4-(2-diethylaminoethoxy)phenylamine and 75 mg (0.30 mmol) of (2-chloro-4-trifluoromethylphenyl)propynoic acid. Yield: 70 mg (53% of theory); melting point: 194° C.-197° C.; C22H22ClF3N2O2 (M=438.88); calc.: molecular ion peak (M+H)+: 439/441; found: molecular ion peak (M+H)+: 439/441; Rf value: 0.35 (silica gel, dichloromethane/methanol=(9:1)).

Provenance & Evidence