HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane methanol → 3-Chloro-4-(2-diethylaminoethoxy)phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | [2-(2-Chloro-4-nitro-phenoxy)-ethyl]-diethyl-amine | HCID 68816504 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Chloro-4-(2-diethylaminoethoxy)phenylamine | HCID 16791676 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from [2-(2-chloro-4-nitrophenoxy)ethyl]diethylamine in methanol in a reaction time of 4.5 hours. Yield: 36.12 g (81.8% of theory); C12H19ClN2O (M=242.75); calc.: molecular ion peak (M+H)+: 243/245; found: molecular ion peak (M+H)+: 243/245; Rf value: 0.36 (silica gel, dichloromethane/methanol (90:10)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-1e32c9ca2e2747508faa6d084ba64cd6 |
| Source note | uspto-grants-2009_09 |