Thionyl Chloride → (2,4-dichlorophenyl)propynoic Acid Chloride

Participants

Reaction Conditions

Reaction Steps

A reaction mixture of 0.34 g (1.58 mmol) of (2,4-dichlorophenyl)propynoic acid and 0.14 mL (1.9 mmol) of thionyl chloride in 15 mL of absolute toluene is stirred for 3 hours at 70° C. and then evaporated down. The residue is taken up in absolute toluene and the solution is evaporated to dryness. This procedure is then repeated once more and the residue is further reacted in its crude state.

Provenance & Evidence