HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane methanol → 2-chloro-N'-[2-(4-methylpiperidin-1-yl)ethyl]benzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | (2-Chloro-4-nitrophenyl)-[2-(4-methylpiperidin-1-yl)ethyl]amine | HCID 55828782 | — |
| Product | 2-chloro-N'-[2-(4-methylpiperidin-1-yl)ethyl]benzene-1,4-diamine | HCID 68817873 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from (2-chloro-4-nitrophenyl)-[2-(4-methylpiperidin-1-yl)ethyl]amine. Yield: 7 g (89.3% of theory); C14H22ClN3 (M=267.80); calc.: molecular ion peak (M+H)+: 268/270; found: molecular ion peak (M+H)+: 268/270; Rf value: 0.6 (Alox, dichloromethane/methanol (49:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-5ef646f006e84f2e8b645677e44c9009 |
| Source note | uspto-grants-2009_09 |