N,N-Diethylethylenediamine → HCID 2829603, compound

HRID 735117Notes

Reaction equation

HRID 735117 reaction equation
[CH2:1]([N:3]([CH2:7][CH3:8])[CH2:4][CH2:5][NH2:6])[CH3:2].[Cl:9][C:10]1[CH:11]=[C:12]([N+:17]([O-:19])=[O:18])[CH:13]=[CH:14][C:15]=1F>ClCCl.CO>[Cl:9][C:10]1[CH:11]=[C:12]([N+:17]([O-:19])=[O:18])[CH:13]=[CH:14][C:15]=1[NH:6][CH2:5][CH2:4][N:3]([CH2:7][CH3:8])[CH2:1][CH3:2]

Participants

4

Reactant 2

HCID 60993N,N-DiethylethylenediamineHCID 676882-Chloro-1-fluoro-4-nitrobenzene

Product 1

HCID 2829603HCID 2829603, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared analogously to Example 4.25.a. from N1,N1-diethylethane-1,2-diamine and 3-chloro-4-fluoronitrobenzene. Yield: 9.2 g (99.1% of theory); C12H18ClN3O2 (M=271.74); calc.: molecular ion peak (M+H)+: 272/274; found: molecular ion peak (M+H)+: 272/274; Rf value: 0.72 (Alox, dichloromethane/methanol (49:1)).

Workup

  1. customPrepared analogously to Example 4.25.a

Sources & evidence

ORD record
ord-a0acb5be2f2c42b1a3df5cfee34ea6af
Source dataset
uspto-grants-2009_09
Patent number
US07592373B2

Reaction notes

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