HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 1-(2-Chloro-4-nitrobenzyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | alpha,2-Dichloro-4-nitrotoluene | HCID 3016511 | — |
| Product | 1-(2-Chloro-4-nitrobenzyl)piperidine | HCID 68819343 | — |
Reaction Steps
Prepared analogously to Example 4.29.a. from 4 mL (40 mmol) of piperidine and 2 g (9.71 mmol) of 2-chloro-4-nitrobenzylchloride. Yield: 2.39 g (97% of theory); C12H15ClN2O2 (M=254.71); calc.: molecular ion peak (M+H)+: 255/257 (Cl); found: molecular ion peak (M+H)+: 255/257 (Cl); Rf value: 0.32 (silica gel, petroleum ether/ethyl acetate (6:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-36a26e61ae2b46ae9fafde6d6e199282 |
| Source note | uspto-grants-2009_09 |