HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-4-methylpiperidine → 3-Methoxy-4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-4-methylpiperidine | HCID 68818421 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 3-Methoxy-4-[2-(4-methylpiperidin-1-yl)ethoxy]phenylamine | HCID 68819112 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]-4-methylpiperidine. Yield: 0.51 g (81.1% of theory); C15H24N2O2 (M=264.37); calc.: molecular ion peak (M+H)+: 265; found: molecular ion peak (M+H)+: 265; Rf value: 0.3 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-259f5d0e7bc24bd68adebac056d7a1da |
| Source note | uspto-grants-2009_09 |