HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-3,5-dimethylpiperidine → 4-[2-(3,5-Dimethylpiperidin-1-yl)ethoxy]-3-methoxyphenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-3,5-dimethylpiperidine | HCID 68819560 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 4-[2-(3,5-Dimethylpiperidin-1-yl)ethoxy]-3-methoxyphenylamine | HCID 68816790 | — |
Reaction Steps
Prepared analogously to Example 3.1.b. from 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]-3,5-dimethylpiperidine. Yield: 0.35 g (96.9% of theory); C15H24N2O2 (M=264.37); calc.: molecular ion peak (M+H)+: 279; found: molecular ion peak (M+H)+: 279; Rf value: 0.3 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-3d2bc9ae9b48443aafa4be2f3be2f837 |
| Source note | uspto-grants-2009_09 |