HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22185405, compound → HCID 57845855, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22185405 | HCID 22185405 | — |
| Reactant | (2-Chloro-4-trifluoromethylphenyl)propynoic acid | HCID 68817422 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 57845855 | HCID 57845855 | — |
Reaction Steps
Prepared analogously to Example 2.3.f. from (2-chloro-4-trifluoromethylphenyl)propynoic acid and 3-methoxy-4-(2-morpholin-4-ylethoxy)phenylamine. Yield: 20 mg (6.9% of theory); melting point: 209° C.-211° C.; C23H22ClF3N2O4 (M=482.89); calc.: molecular ion peak (M+H)+: 483/485; found: molecular ion peak (M+H)+: 483/485; Rf value: 0.5 (silica gel, dichloromethane/methanol (9:1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-909f457a1d9d4ada93bcb1dff258ad20 |
| Source note | uspto-grants-2009_09 |