HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyridin-3-yl)prop-2-ynoic acid → HCID 68818550, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyridin-3-yl)prop-2-ynoic acid | HCID 339277 | — |
| Reactant | 3-Chloro-4-(2-diethylaminoethoxy)phenylamine | HCID 16791676 | — |
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Product | HCID 68818550 | HCID 68818550 | — |
Reaction Steps
Prepared analogously to Example 2.3.f. from pyridin-3-ylpropynoic acid and [2-(2-chloro-4-aminophenoxy)ethyl]diethylamine. Yield: 0.42 g (66.4% of theory); melting point: 118° C.-120° C.; C20H22ClN3O2 (M=371.86); calc.: molecular ion peak (M+H)+: 372/374; found: molecular ion peak (M+H)+: 372/374; Rf value: 0.4 (silica gel, dichloromethane/methanol/ammonia (9:1:0.1)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592373B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-d3a1dbf500ba4b27a27a1d9a4ea782fb |
| Source note | uspto-grants-2009_09 |